My research goal is to learn how necrotrophic bacterial pathogens cause disease in plants. My lab focuses on Pectobacterium and Dickeya, which are broad host range bacterial pathogens and we study how these bacteria infect potato and how to best detect these pathogens in potato and in the environment. We are also interested in other high impact potato pathogens, especially Potato virus Y, and are currently working on projects related to virus resistance and detection in potato.
Courses I Teach
The course provides an overview of the broad range of interactions that bacteria have
with plants, with an emphasis on interactions leading to disease. Particular emphasis will
be on the major groups of plant pathogenic bacteria, the diseases they cause, and how
they cause various disease phenotypes. This course builds upon basic concepts
provided in an introductory plant pathology course, and assumes a basic knowledge of
Sundin, G. W., N. Wang, A. O. Charkowski, L. F. Castiblanco, H. Jia, and Y. Zhao. 2016. Perspectives on the transition from bacterial phytopathogen genomics studies to applications enhancing disease management: from promise to practice. Phytopathology 106:1071-1082.
Charkowski, A. O. 2015. Biology and Control of Pectobacterium in Potato. Amer. J. Potato Res. 92:128-137.
Sharma-Thomas, S., A. Abdurahman, S. Ali, J. Andrade-Piedra, A. O. Charkowski, D. Crook, M. Kadian, P. Kromann, Sarina, P. C. Struik, L. Torrance, K. A. Garret, and G. A. Forbes. 2016. Seed tuber degeneration in potato: need for a new research and development paradigm to mitigate the problem in developing countries. Plant Pathology 65:3-16.
Fulladolsa, A. C., F. M. Navarro, R. Kota, K. Severson, J. P. Palta, and A. O. Charkowski. 2015. Application of marker assisted selection for Potato virus Y resistance in the University of Wisconsin Potato Breeding Program. Amer. J. Potato Res. 92:444-450.
Ma, B., A. O. Charkowski, J. D. Glasner, and N. T. Perna. 2014. Identification of host-microbe interaction factors in the genomes of soft rot-associated pathogens Dickeyadadantii 3937 and Pectobacterium carotovorum WPP14 with supervised machine learning. BMC Genomics 15:Article 508
Mattupalli, C., J. D. Glasner, and A. O. Charkowski. 2014. A draft genome sequence reveals the Helminthosporium solani arsenal for cell wall degradation. Amer. J. Potato Res. 91:517-524.
Guenthner, J. F., A. Charkowski, R. Genger, and G. Greenway. 2014. Varietal differences in minituber production costs. Amer. J. Potato Res. 91:376-379.
Frost, K. E., R. L. Groves, and A. O. Charkowski. 2013. Integrated control of potato pathogens through seed potato certification and provision of clean seed potatoes. Plant Disease. 97:1268-1280 (invited feature article).
Hogan, C. B. M. Mole, S. R. Grant, D. K. Willis, and A. O. Charkowski. 2013. The type III secreted effector DspE is required early in Solanum tuberosum leaf infection by Pectobacterium carotovorum to elicit cell death, and requires Wx(3-6)D/E motifs. PLoS ONE 8: e65534. doi:10.1371/journal.pone.0065534.
Mattupalli, C., R. K. Genger, A. O. Charkowski. 2013. Detection of Helminthosporium solaniand Colletotrichum coccodes in organically grown asymptomatic and symptomatic potatoes. Amer. J. Potato Res. 90:369-377.
Fulladolsa, A. C., R. Kota, and A. O. Charkowski. 2013. Optimization of a chemiluminescent dot-blot immunoassay for detection of potato viruses. Amer. J. Potato Res. 90:306-312.
Kwan, G., A. O. Charkowski and J. D. Barak. 2013. Salmonella enterica suppresses Pectobacterium carotovorum subsp. carotovorum population and soft rot progression by attenuating environmental alkalinization. MBio Feb 12;4(1):e00557-12.
Babujee, L., Apodaca, J. Balakrishnan, P. Liss, P. J. Kiley, A. O. Charkowski., J. D. Glasner, N. T. Perna. 2012. Evolution of the metabolic and regulatory networks associated with oxygen availability in two phytopathogenic enterobacteria. BMC Genomics. 13:110.
Charkowski et al. 2012. The role of secretion systems and small molecules in soft rot Enterobacteriaceae pathogenicity. Ann. Rev. Phytopathol. 50:425-449.