Molecular Plant-Microbe Interactions
Office: C203 Plant Sciences
Lab: E106 Plant Sciences
Many plant traits, such as disease resistance, biomass accumulation, yield, health benefits, etc., are controlled by multiple genes in Quantitative Trait Loci (QTL). Although they govern important plant traits, little is known about the genes that control QTL. Research in the Leach lab is focused on characterizing the genes governing two types of plant QTL, those involved in broad-spectrum, durable disease resistance and those involved in biomass accumulation. The long term goal is to identify target points for plant modification to improve these traits for sustainable crop production. Each of our projects involves rice (Oryza sativa); we have contributed to the development of genomic and genetic resources that make rice an ideal monocot model crop plant. We use different bacterial and fungal pathogens to understand disease resistance mechanisms. All current projects involve collaborations with other labs in the USA and internationally.
Verdier V, Triplett L, Hummel A, Corral R, Cernadas A, Schmidt, CL, Bogdanove A, Leach JE*. 2012. TAL effectors expressed individually targeting OsSWEET genes enhance virulence on diverse rice varieties when in a TAL effector-deficient strain of Xanthomonas oryzae. New Phytologist 196:1197-1207. doi: 10.1111/j.1469-8137.2012.04367.x.
Kumar A, A Henderson, GM Forster, AW Goodyear, TL Weir, JE Leach, SW Dow, EP Ryan. 2012. Dietary rice bran promotes resistance to Salmonella enterica serovar Typhimurium colonization in mice. BMC Microbiol. 12(1):71 doi:10.1186/1471-2180-12-71
Manosalva, P, M Bruce, JE Leach*. 2011. Rice 14-3-3 protein (GF14e) affects cell death and disease resistance. Plant J. 68:777-787. doi: 10.1111/j.1365-313X.2011.04728.x
Triplett, L, JP Hamilton, CR Buell, NA Tisserat, V Verdier, F Zink, JE Leach*. 2011. Genomic Analysis of Xanthomonas oryzae from US rice reveals substantial divergence from known X. oryzae pathovars. Appl. Environ. Microbiol. 77:3930-3937.
Jahn, C, J McKay, R Mauleon, J Stephens, K McNally, D Bush, H Leung, J Leach*. 2011. Genetic variation in biomass traits among 20 diverse rice varieties. Plant Physiol 155(1):157-68.
Feuillet, C, JE Leach, J Rogers, P S Schnable, K Eversole. 2011. Crop genome sequencing: lessons and rationales. Trends Plant Sci 16:77-88. doi:10.1016/j.tplants.2010.10.005.
Webb, K, I Oña, JF Bai, TW Mew, CM Vera Cruz, JE Leach*. 2010. A benefit of high temperature: Increased effectiveness of a rice bacterial blight resistance gene. New Phytologist 185: 568–576. doi: 10.1111/j.1469-8137.2009.03076.x